1. Signaling Pathways
  2. Anti-infection
  3. Parasite

Parasite

Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-W777922
    Nifursol-15N2,d2
    Nifursol-15N2,d2 is the deuterium and 15N-labeled Nifursol (HY-B1703). Nifursol is an orally active veterinary antibiotic. Nifursol inhibits Histomonas meleagridis. Nifursol prevents histomoniasis in turkeys. Nifursol is widely used in studies of Escherichia coli gastroenteritis in Salmonella-infected poultry and aquatic animals.
    Nifursol-<sup>15</sup>N<sub>2</sub>,d<sub>2</sub>
  • HY-168570
    Insecticidal agent 16
    Inhibitor
    Insecticidal agent 16 (compound A21) is a potent insecticidal agent. Insecticidal agent 16 shows insecticidal activities against Plutella xylostella and Spodoptera frugiperda with LC50 values of 1.2 and 13.2 µg/mL, respectively.
    Insecticidal agent 16
  • HY-138502
    Melarsomine
    Inhibitor
    Melarsomine is a trivalent arsenical compound used as an adulticide. Melarsomine can be used for the reserach of canine heartworm disease and other helminth infections.
    Melarsomine
  • HY-14603R
    Clioquinol (Standard)
    Clioquinol (Standard) is the analytical standard of Clioquinol. This product is intended for research and analytical applications. Clioquinol (Iodochlorhydroxyquin) is a topical antifungal agent with anticancer activity. Clioquinol acts as an oral antimicrobial agent for the research of diarrhea and skin infections. Antibiotic.
    Clioquinol (Standard)
  • HY-79504
    Ferrocene
    Inhibitor ≥98.0%
    Ferrocene is an important structural core in bioorganometallic chemistry because of its inherent stability, excellent redox properties, and low toxicity. Ferrocene has antimalarial and anticancer properties.
    Ferrocene
  • HY-B1751S
    Quinidine-d3
    Inhibitor
    Quinidine-d3 is the deuterium labeled Quinidine. Quinidine is an antiarrhythmic agent for the treatment of abnormal heart rhythms and also malaria.
    Quinidine-d<sub>3</sub>
  • HY-117179
    Endosulfan sulfate
    Inhibitor
    Endosulfan sulfate is the major metabolite of the insecticide Endosulfan, used for various crops. Endosulfan sulfate is more toxic and persistent than Endosulfan.
    Endosulfan sulfate
  • HY-B0803S
    Lumefantrine-d18
    Inhibitor
    Lumefantrine-d18 is the deuterium labeled Lumefantrine, which is an antimalarial agent.
    Lumefantrine-d<sub>18</sub>
  • HY-W014394R
    Vanillyl butyl ether (Standard)
    Protoporphyrin IX (Standard) is the analytical standard of Protoporphyrin IX. This product is intended for research and analytical applications. Protoporphyrin IX is a final intermediate in the heme biosynthetic pathway, which acts as a radiation sensitizer enhancing ROS generation even in a hypoxic state and inducing DNA damage. Protoporphyrin IX also acts as a photo sensitizer undergoing photobleaching that occurs through direct degradation by light irradiation. Protoporphyrin IX is formed and accumulated following 5-aminolevulinic acid (5-ALA) (HY-W000450) administration in the tumor cells of rats. Protoporphyrin IX causes selective improvement of basal cell carcinoma when activated red fluorescence of a peak wavelength at 405 nm. Protoporphyrin IX is promising for research of sonodynamic and photodynamic agents for a wide range of cancers, such as bladder cancer and nodular basal cell carcinoma.
    Vanillyl butyl ether (Standard)
  • HY-B1004R
    Dinitolmide (Standard)
    Inhibitor
    Dinitolmide (Standard) is the analytical standard of Dinitolmide. This product is intended for research and analytical applications. Dinitolmide (Zoalene), a fodder additive for poultry, has anti-coccidial effect. Dinitolmide can be used to prevent infections induced by Eimeria, such as Eimeria tenella, Eimeria necatrix, Eimeria brunette, and so on.
    Dinitolmide (Standard)
  • HY-P5696
    Xenopsin precursor fragment
    Inhibitor
    Xenopsin precursor fragment is an antimicrobial peptide, and has antibacterial/antifungal (10-500 μg/mL) and anti-protozoal (MIC: 2-20 μg/mL) activity.
    Xenopsin precursor fragment
  • HY-N3247
    Monomethyl kolavate
    Inhibitor
    Monomethyl kolavate is a Trypanosoma brucei GAPDH enzyme (TbGAPDH) inhibitor with theIC50 value of 2 µM.
    Monomethyl kolavate
  • HY-169445
    (±)-Meclonazepam
    Control
    (±)-Meclonazepam ((±)-Ro 11-3128) is the racemate of Meclonazepam (HY-101725). Meclonazepam (Ro 11-3128) is a benzodiazepine compound with anxiolytic effect. Meclonazepam exhibits antischistosomal activity against S. mansoni.
    (±)-Meclonazepam
  • HY-144098
    HDAC8-IN-2
    Inhibitor
    HDAC8-IN-2 (compound 5o) is a potent HDAC8 inhibitor, with IC50 values of 0.27 and 0.32 μM for smHDAC8 (Schistosoma mansoni histone deacetylase 8) and hHDAC8, respectively. HDAC8-IN-2 shows significant killing of the schistosome larvae. HDAC8-IN-2 markedly impairs egg laying of adult worm pairs.
    HDAC8-IN-2
  • HY-N6251
    Cratoxylone
    Inhibitor
    Cratoxylone, isolated from the bark of Cratoxylum Cochinchinense, possesses antiplasmodial activity.
    Cratoxylone
  • HY-139672
    BRD5018
    Inhibitor
    BRD5018 is an antimalarial agent. BRD5018 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    BRD5018
  • HY-N3378
    Lipiferolide
    Inhibitor
    Lipiferolide is an antiplasmodial agent (IC50: 1.8 μg/mL) that can be isolated from Liriodendron tulipifera. Lipiferolide also inhibits FPTase, and has antitumor activity.
    Lipiferolide
  • HY-114614
    Clenpirin
    Inhibitor
    Clenpirin is a insecticide against cattle ticks Boophilus microplus. Clenpirin exhibits slightly toxicity to rats with LD50 of 3050 mg/kg.
    Clenpirin
  • HY-161666
    mCMY416
    Inhibitor
    mCMY416 is an orally active and blood brain barrier (BBB) permeability apicomplexan phenylalanine tRNA synthetase inhibitor, and shows antiparasitic activity .
    mCMY416
  • HY-159097
    T.cruzi-IN-4
    Inhibitor
    T.cruzi-IN-4 (Compound 21) is an anti-parasitic agent. T.cruzi-IN-4 inhibits the trypomastigote and amastigote form of Trypanosoma cruzi with IC50 of 0.033 μM (120 h), T.cruzi-IN-4 inhibits the promastigote and amastigote form of Leishmania infantum with IC50 of 28.74 and 61.82 μM. T.cruzi-IN-4 inhibits Leishmania amazonensis promastigote form with IC50 of 18.38 μM.
    T.cruzi-IN-4

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